Analysis of CYP2C19 Genetic Polymorphism in a Large Ethnic Hakka Population in Southern China

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Analysis of CYP2C19 Genetic Polymorphism in a Large Ethnic Hakka Population in Southern China

BACKGROUND Cytochrome P450 (CYP) 2C19 is an enzyme involved in the bioactivation of various important therapeutic drugs, from pro-drugs to an active inhibitor of platelet action. Variants in the CYP2C19 gene influence the pharmacokinetics and clinical response to antiplatelet drugs such as clopidogrel; however, there is no available data about the genetic variation of CYP2C19 in the Hakka popul...

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Genetic Polymorphism of CYP2C19 in Pakistani Population

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ژورنال

عنوان ژورنال: Medical Science Monitor

سال: 2017

ISSN: 1643-3750

DOI: 10.12659/msm.905337